Lecture 6

We start by considering crosses between inbred lines. The analysis of such crosses illustrates many of the fundamental features of QTL mapping without the additional complications that arise with outbred populations. Although inbred line crosses are uncommon in animal breeding (outside of rats and mice), crosses between widely-differing lines are often treated as an inbred line cross, as we assume that marker and QTL allele frequencies are very different between the lines.